objective: seeking for fertility after previous vasectomy is increasing. vasectomy may break the blood testis barrier and in this way the level of antisperm antibody increases. it is suggested that increase in antisperm antibody decreases spontaneous pregnancy even after successful vasovasostomy. in this study we evaluated antisperm antibody formation 3 months after vasectomy. method: this stud...

background: antifertility effect of naturally occuring antisperm antibody (asa) in infertile couples and studies on experimental immunization of various animals with sperm antigens represents asa as immunocontraceptive target. despite extensive research on the effects of different factors on sperm immunogenecity and asa production variable result have been reported. objective: to study whole sp...

introduction: antifertility effects of naturally occuring antisperm antibody (asa) in infertile couples and studies on experimental immunization of various animals with sperm antigens represent asa as an immunocontraceptive target. the effects of different factors on sperm immunogenecity and asa production have been studied and different results have been reported. in this study, whole sperm im...

OBJECTIVE To investigate whether Chinese medicine Tai-bao could inhibit antisperm antibody in experimental mice. METHODS The experimental immunoinfertility mice were due to antisperm antibody induced by injection of human sperm membrane antigens. The experimental immuno-infertile mice used in the present study were divided into four groups including Tai-bao high dose group (46.8 g.kg-1.d-1), ...

OBJECTIVE:We evaluated the effectiveness of spermwashing using the discontinuous two-layer density gradient centrifugation method to remove antisperm antibodies attached to the sperm surface. METHOD: We prospectively enrolled sixty-six men with unexplained infertility who were seeking evaluation. Each patient delivered one semen specimen for the study. We determined antisperm antibody levels us...

background: infertility is one of the common problems seen in couples of reproductive age. presence of antisperm antibodies in semen and serum are amongst the causes of immunoinfertility. this study was performed to determine antisperm antibodies in cervicovaginal secretions and serum of infertile women and also measure serum levels of immunoglobulins (igg, igm and iga). methods: the study cons...

OBJECTIVE To determine the usefulness of and cost-effectiveness of antisperm antibody testing in the prediction of poor fertilization rates in couples undergoing IVF. DESIGN Retrospective cohort study. SETTING A hospital-based reproductive endocrinology and infertility practice. PATIENT(S) Male partners of 251 couples undergoing IVF between 1992 and 1997. MAIN OUTCOME MEASURE(S) Fertili...

The presence of antiidiotypic antibodies (ab-2) to sperm was investigated in the sera of fertile, infertile, and virgin women using sperm-specific anti-FA-1 monoclonal antibody Fab'.ab-2 were detected in 71% (17/24) of sera from fertile women and in none (0/12) of the sera from virgin females by the enzyme-linked immunosorbent assay, Western blot procedure, and immunoprecipitation procedure. Se...

The presence of antiidiotypic antibodies (ab-2) to sperm was investigated in the sera of fertile, infertile, and virgin women using sperm-specific anti-FA-1 monoclonal antibody Fab'. ab-2 were detected in 71% (17 /24) of sera from fertile women and in none (0/12) of the sera from virgin females by the enzymelinked immunosorbent assay, Western blot procedure, and immunoprecipitation procedure. S...

: Presence of antisperm antibodies (ASAs) in infertility and their adverse effects on fertility is a matter of controversy. The aims of this study were to determine the percentage of antibody positive sperms and rate of ASA positive sera in both fertile and infertile men and women, and to find the association between these antibodies and infertility. Methods: This study consisted of 29 fertile ...